Atorvastatin Cyclic (Fluorophenyl) Sodium Salt Impurity

CAS: 1315629-79-8

Ref. TR-A791820

Product Information

• Name: Atorvastatin Cyclic (Fluorophenyl) Sodium Salt Impurity
• Synonyms: 1b-(4-Fluorophenyl)hexahydro-ß,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine-3-butanoic Acid Sodium Salt (1:1), Atorvastatin FX1 IMpurity, Atorvastatin Cyclic (Fluorophenyl) Sodium, Atorvastatin epoxy pyrrolooxazin 7hydroxy analog, 1b-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine-3-butanoic acid sodium salt, Atorvastatin Cyclic Sodium Salt (Fluorophenyl) Impurity, 1b-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-Methylethyl)-1a-phenyl-7a-[(phenylaMino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine-3-butanoic Acid SodiuM, ATV-FX1 sodiuM salt

Description

Stability Hygroscopic
Applications A photodegadation product of Atorvastatin (a cyclic impurity of Atorvastatin).
References Roger, D., et al.: Clin. Exp. Dermatol., 19, 88 (1994), Cosa, G., et al.: Photochem. Photobiol., 80, 159 (2004), Kerwin, B., et al.: J. Pharm. Sci., 96, 1468 (2007),

• Brand: TRC

Chemical properties

• Molecular weight: 612.62
• Formula: C₃₃H₃₄FN₂O₇·Na
• Color/Form: Neat
• InChI: InChI=1S/C33H35FN2O7.Na/c1-21(2)32(41)31(29(40)35-25-11-7-4-8-12-25)30(43-31,22-9-5-3-6-10-22)33(23-13-15-24(34)16-14-23)36(32)18-17-27(42-33)19-26(37)20-28(38)39;/h3-16,21,26-27,37,41H,17-20H2,1-2H3,(H,35,40)(H,38,39);/q;+1/p-1
• SMILES: CC(C)C1(O)N2CCC(CC(O)CC(=O)[O-])OC2(c2ccc(F)cc2)C2(c3ccccc3)OC12C(=O)Nc1ccccc1.[Na+]