Estimated delivery in United States, on Wednesday 15 Jan 2025
Product Information
Name:
AZ 5104 Hydrochloride
Synonyms:
- N-(5-((4-(1H-Indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide HCl
Description:
Stability Hygroscopic
Applications The hydrochloride salt of AZ 5104 (A795170), which is a derivative of AZD 9291 (A808075) and a selective EGFR inhibitor (epidermal growth factor receptor), used in the treatments of nonsmall-cell lung cancer (NSCLC).
References Finlay, M.R.V., et al.: J. Med. Chem., 57, 8249 (2014);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
522.04
Formula:
C27H31N7O2·HCl
Color/Form:
Neat
InChI:
InChI=1S/C27H31N7O2.ClH/c1-6-26(35)30-22-15-23(25(36-5)16-24(22)34(4)14-13-33(2)3)32-27-28-12-11-21(31-27)19-17-29-20-10-8-7-9-18(19)20;/h6-12,15-17,29H,1,13-14H2,2-5H3,(H,30,35)(H,28,31,32);1H
InChI key:
InChIKey=GGGIAJZFMFTICN-UHFFFAOYSA-N
SMILES:
C=CC(=O)Nc1cc(Nc2nccc(-c3c[nH]c4ccccc34)n2)c(OC)cc1N(C)CCN(C)C.Cl
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-A795180 AZ 5104 Hydrochloride
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