Product Information
- (1S,3S,5S)-2-Azabicyclo[3.1.0]Hexane-3-Carbonitrile
Applications Saxagliptin hydrochloride monohydrate, an anti-diabetic drug can be synthesized using a coupling reaction of (S)-phthalimido-(3-hydroxy-adamantan-1-yl)acetic acid with (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-3-nitrile followed by removal of the phthalimide protecting group and treatment with HCl.
References Kovi, Ravishanker, et al.: Apicore, LLC, WO 2012162507 (2012)
Chemical properties
Technical inquiry about: TR-A795335 (1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carbonitrile
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