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2,4-Bis(trimethylsilyl)cytosine
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2,4-Bis(trimethylsilyl)cytosine

CAS: 18037-10-0

Ref. TR-B101910

5g
1,063.00 €
Estimated delivery in United States, on Friday 21 Jun 2024

Product Information

Name:
2,4-Bis(trimethylsilyl)cytosine
Controlled Product
Synonyms:
  • 2-(Trimethylsiloxy)-4-[(trimethylsilyl)amino]-pyrimidine
  • N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamine
  • O,N-Bis(trimethylsilyl)cytosine
  • 1,1,1-Trimethyl-N-[2-[(trimethylsilyl)oxy]pyrimidin-4-yl]silanamine
  • 4-Pyrimidinamine, N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-
  • Bis(Trimethylsilyl)Cytosine
  • Bistrimethylsilylcytosine
  • N-(Trimethylsilyl)-2-[(Trimethylsilyl)Oxy]-4-Pyrimidinamin
  • N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]pyrimidin-4-amine
  • O2,N4-Bis(trimethylsilyl)cytosine
  • See more synonyms
  • Pyrimidine, 2-(trimethylsiloxy)-4-[(trimethylsilyl)amino]-
Description:

Applications 2,4-Bis(trimethylsilyl)cytosine is an intermediate used in the synthesis of 1’-Epi Gemcitabine Hydrochloride (E588510), which is an α-Anomer of Gemcitabine.
References Hertel, L.W., et al.: Cancer Res., 50, 4417 (1990), Abbruzzese, J.L., et al.: J. Clin. Oncol., 9, 491 (1991), Ruiz, V.W.T., et al.: Biochem. Pharmacol., 46, 762 (1993),

Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
255.464
Formula:
C10H21N3OSi2
InChI:
InChI=1S/C10H21N3OSi2/c1-15(2,3)13-9-7-8-11-10(12-9)14-16(4,5)6/h7-8H,1-6H3,(H,11,12,13)
InChI key:
InChIKey=IWEHUWMQLZFGLL-UHFFFAOYSA-N
SMILES:
C[Si](C)(C)Nc1ccnc(O[Si](C)(C)C)n1
MDL:
Melting point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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