Estimated delivery in United States, on Tuesday 11 Jun 2024
Product Information
Name:
Belinostat Glucuronide
Synonyms:
- (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(((E)-3-(3-(N-phenylsulfamoyl)phenyl)acrylamido)oxy)tetrahydro-2H-pyran-2-carboxylic Acid
CAS:
Description:
Applications Belinostat Glucuronide is the major metabolite of Belinostat. Belinostat (B131400) is a novel histone deacetylase 3 selective inhibitor, which protects the β cells from cytokine-induced apoptosis.
References Wang, L., et al.: PLoS One, 8, 54522 (2013); Chou, D.H., et al.: Chem. Biol., 19, 669 (2012); Hwang, J.J., et al.: Inves. New. Drugs., 30, 1434 (2012); Dizon, D.S., et al.: Gynecol. Oncol., 125, 367 (2012);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
494.47
Formula:
C21H22N2O10S
Color/Form:
Neat
InChI:
InChI=1S/C21H22N2O10S/c24-15(22-33-21-18(27)16(25)17(26)19(32-21)20(28)29)10-9-12-5-4-8-14(11-12)34(30,31)23-13-6-2-1-3-7-13/h1-11,16-19,21,23,25-27H,(H,22,24)(H,28,29)/b10-9+/t16-,17-,18+,19-,21-/m0/s1
InChI key:
InChIKey=FZFPHALYAMPZAH-UAHLBMKISA-N
SMILES:
O=C(/C=C/c1cccc(S(=O)(=O)Nc2ccccc2)c1)NO[C@@H]1O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]1O
MDL:
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EINECS:
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HS code:
Technical inquiry about: TR-B131405 Belinostat Glucuronide
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