Bendamustine

CAS: 16506-27-7

Ref. TR-B132558

Product Information

• Name: Bendamustine
• Synonyms: 2-Benzimidazolebutyric acid, 5-[bis(2-chloroethyl)amino]-1-methyl- (8CI), 4-[5-[Bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid, ?-[1-Methyl-5-[bis(ß-chloroethyl)amino]-2-benzimidazolyl]butyric acid, 1H-Benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1-methyl-, 2-Benzimidazolebutyric acid, 5-[bis(2-chloroethyl)amino]-1-methyl-, 4-{5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl}butanoic acid, 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid, ω-[1-Methyl-5-[bis(β-chloroethyl)amino]-2-benzimidazolyl]butyric acid
• CAS: 16506-27-7

Description

Applications Bendamustine is an intermediate in the synthesis of Bendamustine 3-Hydroxyprop-2-yl Ester (B132550), which is an impurity of anticancer drug Bendamustine Hydrochloride (B132500).
References Bremer, K., et al.: Tumordiagn. Ther., 17, 1 (1996); Barman Balfour, J.A., et al.: Drugs, 61, 631 (2001);

• Brand: TRC

Chemical properties

• Molecular weight: 358.263
• Formula: C₁₆H₂₁Cl₂N₃O₂
• Color/Form: Neat
• InChI: InChI=1S/C16H21Cl2N3O2/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23/h5-6,11H,2-4,7-10H2,1H3,(H,22,23)
• InChI key: InChIKey=YTKUWDBFDASYHO-UHFFFAOYSA-N
• SMILES: Cn1c(CCCC(=O)O)nc2cc(N(CCCl)CCCl)ccc21