Benfotiamine-Amide

CAS: 22457-89-2

Ref. TR-B136003

Product Information

• Name: Benfotiamine-Amide
• Synonyms: (E)-S-2-(N-[4-benzamido-2-methylpyrimidin-5-yl)methyl)formamido]-5-(phosphonooxy)pent-2-en-3-yl-benzothioate, 8088Cb, Benfothiamine, Benfotiamine, Benzenecarbothioic acid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propen-1-yl] ester, Benzenecarbothioic acid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propenyl] ester, Benzoic acid, thio-, S-ester with N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide dihydrogen phosphate (ester), Benzoylthiamine O-monophosphate, Benzoylthiamine monophosphate, Berdi, Betivina, Bietamine, Biotamin, Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)-, S-benzoate O-(dihydrogen phosphate), Milgamma, N-((4-Amino-2-Methyl-5-Pyrimidinyl)Methyl)-N-(4-Hydroxy-2-Mercapto-1-Methyl-1-Butenyl)Formamide-S-Benzoate Dihydrogen Phosphate, N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(4-hydroxy-2-mercapto-1-methyl-1-butenyl)formamide S-benzoate O-phosphate, Neurostop, Nitanevril, S-Benzoylthiamine monophosphate, S-[2-{[(4-amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}-5-(phosphonooxy)pent-2-en-3-yl] benzenecarbothioate, S-{(1E)-2-{[(4-amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}-1-[2-(phosphonooxy)ethyl]prop-1-en-1-yl} benzenecarbothioate, S-{(1Z)-2-{[(4-amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}-1-[2-(phosphonooxy)ethyl]prop-1-en-1-yl} benzenecarbothioate, Tabiomyl, Vitanevril
• CAS: 22457-89-2

Description

Stability Hygroscopic
Applications Benfotiamine-Amide is an analog of Benfotiamine, which is a Vitamin B1 analog. Synthetic S-acyl derivative of Thiamine (T344185).
References Stracke, H., et al.: Exper. Clin. Endocrinol., Diabetes, 116, 600 (2008), Gohil, V., et al.: Nat., Biotechnol., 28, 249 (2010),

• Brand: TRC

Chemical properties

• Molecular weight: 570.55
• Formula: C₂₆H₂₇N₄O₇PS
• Color/Form: Neat
• InChI: InChI=1S/C26H27N4O7PS/c1-18(23(13-14-37-38(34,35)36)39-26(33)21-11-7-4-8-12-21)30(17-31)16-22-15-27-19(2)28-24(22)29-25(32)20-9-5-3-6-10-20/h3-12,15,17H,13-14,16H2,1-2H3,(H2,34,35,36)(H,27,28,29,32)/b23-18-
• InChI key: InChIKey=BQLNLRCYOFCJOY-NKFKGCMQSA-N
• SMILES: C/C(=C(\CCOP(=O)(O)O)SC(=O)c1ccccc1)N(C=O)Cc1cnc(C)nc1NC(=O)c1ccccc1