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Product Information
Name:
(S)-1,4-Benzodioxan-2-carboxypiperazine
Controlled Product
Synonyms:
- [(2S)-2,3-Dihydro-1,4-benzodioxin-2-yl]-1-piperazinyl-methanone
- Methanone, [(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]-1-piperazinyl-
Description:
Applications (S)-1,4-Benzodioxan-2-carboxypiperazine is the key chiral intermediate for the synthesis of (S)-doxazosin (D537500, Mesylate salt), a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.
References Fang, Q., et al.: Tetrahedron Asym., 12, 2169 (2001); Elliott, H.L., et al.: Brit. J. Clin. Pharmacol., 13, 699 (1982); de Leeuw, P.W., et al.: Eur. J. Clin. Pharmacol., 23, 397 (1982)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
248.28
Formula:
C13H16N2O3
Color/Form:
Neat
InChI:
InChI=1S/C13H16N2O3/c16-13(15-7-5-14-6-8-15)12-9-17-10-3-1-2-4-11(10)18-12/h1-4,12,14H,5-9H2/t12-/m0/s1
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-B200060 (S)-1,4-Benzodioxan-2-carboxypiperazine
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