(2S,5S)-5-Benzyl-3,6-dioxo-2-piperazineacetic Acid

CAS: 5262-10-2

Ref. TR-B276305

Product Information

• Name: (2S,5S)-5-Benzyl-3,6-dioxo-2-piperazineacetic Acid
• Synonyms: Aspartame Imp. A (EP), Aspartame USP Related Compound A, Aspartame USP RC A, 2-(5-Benzyl-3,6-dioxopiperazin-2-yl)acetic Acid, Diketopiperazine, Aspartame Related Compound A, Aspartame Impurity A, (2S,5S)-3,6-Dioxo-5-(phenylmethyl)-2-piperazineacetic acid, 2-Piperazineacetic acid, 3,6-dioxo-5-(phenylmethyl)-, (2S,5S)-, 2-Piperazineacetic acid, 3,6-dioxo-5-(phenylmethyl)-, (2S-cis)-, 2-Piperazineacetic acid, 5-benzyl-3,6-dioxo-, 5-Benzyl-3,6-Dioxo-2-Piperazineacetic Acid, Cycloaspartylphenylalanine
• CAS: 5262-10-2

Description

Impurity Aspartame EP Impurity A/ Aspartame USP Related Compound A
Applications (2S,5S)-5-Benzyl-3,6-dioxo-2-piperazineacetic Acid (Aspartame EP Impurity A) is the diketopiperazine impurity of the sweetening agent Aspartame (A790015). It is also found in in processed cocoa powder.
References Ciranni Signoretti, E. et al.: Boll. Chim. Farmac., 122, 289 (1983); Prudel, M. et al.: Nahrung, 29, 381 (1985); Bonvehi, J.S. et al.: Eur. Food. Res. Technol., 210, 189 (2000);

• Brand: TRC

Chemical properties

• Molecular weight: 262.26
• Formula: C₁₃H₁₄N₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C13H14N2O4/c16-11(17)7-10-13(19)14-9(12(18)15-10)6-8-4-2-1-3-5-8/h1-5,9-10H,6-7H2,(H,14,19)(H,15,18)(H,16,17)/t9-,10-/m0/s1
• InChI key: InChIKey=VNHJXYUDIBQDDX-UWVGGRQHSA-N
• SMILES: O=C(O)C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC1=O