2-Benzyloxy-5-bromoacetylbenzoic Acid Methyl Ester

CAS: 27475-14-5

Ref. TR-B288025

Product Information

• Name: 2-Benzyloxy-5-bromoacetylbenzoic Acid Methyl Ester
• Synonyms: Methyl 2-Benzyloxy-5-(bromoacetyl)benzoate, 2-Benzyloxy-5-(2-bromoacetyl)benzoic Acid Methyl Ester, 5-(bromoacetyl)-2-(phenylmethoxy)benzoic Acid Methyl Ester, 2-(Benzyloxy)-5-(bromoacetyl)benzoic Acid Methyl Ester, 2-Benzyloxy-5-bromoacetylbenzoic acid methyl ester, Methyl 5-(2-bromoacetyl)-2-(phenylmethoxy)benzoate, Benzoic acid, 5-(bromoacetyl)-2-(phenylmethoxy)-, methyl ester, Benzoic acid, 5-(2-bromoacetyl)-2-(phenylmethoxy)-, methyl ester, Benzoic acid, 2-(benzyloxy)-5-(bromoacetyl)-, methyl ester, Methyl 2-(benzyloxy)-5-(bromoacetyl)benzoate

Description

Applications 2-Benzyloxy-5-bromoacetylbenzoic Acid Methyl Ester is an intermediate in the synthesis of Salmeterol (S090100), a β2-Adrenergic agonist.
References Johnson, M.: Lung, 168, Suppl., 115 (1990), Ullman, A., et al.: Am. Rev. Resp. Dis., 142, 571 (1990), Twentyman, O.P., et al.: Lancet, 336, 1338 (1990)

• Brand: TRC

Chemical properties

• Molecular weight: 316.199
• Formula: C₁₇H₁₅BrO₄
• Color/Form: White Solid
• InChI: InChI=1S/C9H17O10P/c1-16-8(12)9(17-2)3-5(10)7(11)6(19-9)4-18-20(13,14)15/h5-7,10-11H,3-4H2,1-2H3,(H2,13,14,15)/t5?,6?,7-,9-/m1/s1
• InChI key: InChIKey=KJQADXROFHHYNJ-SFCRDCIYSA-N
• SMILES: COC(=O)[C@@]1(OC)CC(O)[C@@H](O)C(COP(=O)(O)O)O1