5-Bromo-6,7-demethylenedeoxypodophyllotoxin

CAS: 93108-15-7

Ref. TR-B293795

Product Information

• Name: 5-Bromo-6,7-demethylenedeoxypodophyllotoxin
• Synonyms: (3aR,9R,9aR)-5-Bromo-6,7-dihydroxy-9-(3,4,5-trimethoxyphenyl)-3a,4,9,9a-tetrahydronaphtho[2,3-c]furan-1(3H)-one
• CAS: 93108-15-7

Description

Applications 5-Bromo-6,7-demethylenedeoxypodophyllotoxin is a derivative of 6,7-Demethylenedeoxypodophyllotoxin (D295560), a metabolite of 4-Deoxypodophyllotoxin (D249500). 4-Deoxypodophyllotoxin is a medicinal herb product isolated from Anthriscus sylvestris Hoffm. It is well known for its antitumor, antiviral, and anti-inflammatory activities. 4-Deoxypodophyllotoxin was also shown to inhibit the passive cutaneous anaphylaxis reaction.
References Lin, C.X., et al.: Planta. Med., 70, 474 (2004); Peng, Xu., et al.: Neurotoxicol., 31, 680 (2010); Kim, Y., et al.: Planta, Med., 68, 271 (2002);

• Brand: TRC

Chemical properties

• Molecular weight: 465.29
• Formula: C₂₁H₂₁BrO₇
• InChI: InChI=1S/C21H21BrO7/c1-26-14-5-9(6-15(27-2)20(14)28-3)16-11-7-13(23)19(24)18(22)12(11)4-10-8-29-21(25)17(10)16/h5-7,10,16-17,23-24H,4,8H2,1-3H3/t10-,16+,17-/m0/s1
• InChI key: InChIKey=LAZVAOGUDDOIMH-HKJPBSJPSA-N
• SMILES: COc1cc([C@@H]2c3cc(O)c(O)c(Br)c3C[C@H]3COC(=O)[C@@H]32)cc(OC)c1OC