Betamethasone 17-Propionate

CAS: 5534-13-4

Ref. TR-B327015

Product Information

• Name: Betamethasone 17-Propionate
• Synonyms: 9-Fluoro-11β,21-dihydroxy-16β-methyl-3,20-dioxopregna-1,4-dien-17-yl Propanoate, (11β,16β)-9-Fluoro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate, Betamethasone 17α-propionate, (11Beta,16Beta)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Propanoate, 226-887-6, Betamethasone 17-propionate, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)-, (11β,16β)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 17-propionate
• CAS: 5534-13-4

Description

Impurity Clobetasol Propionate EP Impurity A / Betamethasone Dipropionate EP Impurity B
Applications Betamethasone 17-Propionate (Clobetasol Propionate EP Impurity A) is a degradation product of Betamethasone. Glucocorticoid.
References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),

• Brand: TRC

Chemical properties

• Molecular weight: 448.52
• Formula: C₂₅H₃₃FO₆
• Color/Form: Off-White
• InChI: InChI=1S/C25H33FO6/c1-5-21(31)32-25(20(30)13-27)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,26)19(29)12-23(18,25)4/h8-9,11,14,17-19,27,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1
• InChI key: InChIKey=ITYMTTQVNYAJAA-XGQKBEPLSA-N
• SMILES: CCC(=O)O[C@]1(C(=O)CO)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C