6-N-Biotinylaminohexyl Isopropyl Phosphorofluoridate, Hemihydrate

CAS: 353754-93-5

Ref. TR-B394900

Product Information

• Name: 6-N-Biotinylaminohexyl Isopropyl Phosphorofluoridate, Hemihydrate
• Synonyms: Phosphorofluoridic acid, 6-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]hexyl 1-methylethyl ester, hydrate (2:1), 6-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]hexyl Phosphorofluoridic Acid 1-Methylethyl Ester Hemihydrate, FP-Biotin, Phosphorofluoridic acid, 6-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]hexyl 1-methylethyl ester, hydrate (2:1)

Description

Stability HIGHLY TOXIC
Applications A potent tool for the inhibition and isolation of Serine Esterases and Proteases. Also a potent inhibitor of a-chymotrypsin.
References Cohen, J., et al.: Meth. Enzymol., 11, 686 (1967), DelMar, E., et al.: Anal. Biochem., 99, 316 (1979), Fukuda, Y., et al.: Eur. J. Pharmacol., 390, 203 (2000), Davies, S., et al.: J. Biol. Chem., 276, 16015 (2001), Quistad, G., et al.: Toxicol. Appl. Pharmacol., 196, 319 (2004),

• Brand: TRC

Chemical properties

• Molecular weight: 953.09
• Formula: C₁₉H₃₅FN₃O₅PS·H₂O
• Color/Form: Neat
• InChI: InChI=1S/2C19H35FN3O5PS.H2O/c2*1-14(2)28-29(20,26)27-12-8-4-3-7-11-21-17(24)10-6-5-9-16-18-15(13-30-16)22-19(25)23-18;/h2*14-16,18H,3-13H2,1-2H3,(H,21,24)(H2,22,23,25);1H2/t2*15-,16-,18-,29?;/m00./s1
• InChI key: InChIKey=KDPHOPZAOAVYRV-VTNPVEBBSA-N
• SMILES: CC(C)OP(=O)(F)OCCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12