Bis(4-hydroxyphenyl)acetic Acid

CAS: 40232-93-7

Ref. TR-B446795

Product Information

• Name: Bis(4-hydroxyphenyl)acetic Acid
• Synonyms: 2,2-Bis(p-hydroxyphenyl)acetic Acid, 2,2-Bis(4-hydroxyphenyl)acetic Acid, 4-Hydroxy-alpha-(4-hydroxyphenyl)benzeneacetic Acid, 4-Hydroxy-alpha-(4-hydroxyphenyl)-benzeneacetic Acid, 2,2-Bis(4-hydroxyphenyl)acetic acid, 2,2-Bis(p-hydroxyphenyl)acetic acid, 4-Hydroxy-α-(4-hydroxyphenyl)benzeneacetic acid, Acetic acid, bis(p-hydroxyphenyl)-, Benzeneacetic acid, 4-hydroxy-alpha-(4-hydroxyphenyl)-, Benzeneacetic acid, 4-hydroxy-α-(4-hydroxyphenyl)-

Description

Applications Bis(4-hydroxyphenyl)acetic Acid is a bis-phenolic derivative formed from O-demethylation and dechlorination of an insecticide, methoxychlor. Also, it is derived from Glyoxylic Acid (G754995), which is used as a reagent in the synthesis of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-L-leucine, a novel nonpeptide chemotype selective for neurotensin receptor 2. Also, used as a reagent in the synthesis of elemonic acid derivatives as Pin 1 inhibitors.
References Satsuma, K., et al.: Appl. Environ. Microbiol., 78, 5313-5319 (2012); Thomas, J.B., et al.: Bioorg. Med. Chem. Lett., 25, 292 (2015); Li, X., et al.: Bioorg. Med. Chem. Lett., 24, 5612 (2014);

• Brand: TRC

Chemical properties

• Molecular weight: 244.24
• Formula: C₁₄H₁₂O₄
• Color/Form: White Solid
• InChI: InChI=1S/C14H12O4/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8,13,15-16H,(H,17,18)
• InChI key: InChIKey=SCBGJZIOPNAEMH-UHFFFAOYSA-N
• SMILES: O=C(O)C(c1ccc(O)cc1)c1ccc(O)cc1