N-tert-Butyloxycarbonyl Silodosin N-oxide
Ref. TR-B465095
| 10mg | Discontinued | ||
| 25mg | Discontinued | ||
| 50mg | Discontinued |
Product Information
Name:
N-tert-Butyloxycarbonyl Silodosin N-oxide
Synonyms:
- 5-((R)-2-((tert-Butoxycarbonyl)(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)-7-carbamoyl-1-(3-hydroxypropyl)indoline 1-Oxide
Description:
Applications N-tert-Butyloxycarbonyl Silodosin N-oxide is an intermediate in the synthesis of Silodosin N-Oxide (S465045) which is an N-oxide metabolite or degradation product of the drug Silodosin (S465000) which is an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy.
References Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995), Murata, S., et al.: J. Urol., 164, 578 (2000),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
611.65
Formula:
C30H40F3N3O7
Color/Form:
Pale brown foam
InChI:
InChI=1S/C30H40F3N3O7/c1-20(16-21-17-22-10-13-36(40,12-7-14-37)26(22)23(18-21)27(34)38)35(28(39)43-29(2,3)4)11-15-41-24-8-5-6-9-25(24)42-19-30(31,32)33/h5-6,8-9,17-18,20,37H,7,10-16,19H2,1-4H3,(H2,34,38)/t20-,36?/m1/s1
InChI key:
InChIKey=AXNFXYHODPANNB-CTGAYHRJSA-N
SMILES:
C[C@H](Cc1cc2c(c(C(N)=O)c1)[N+]([O-])(CCCO)CC2)N(CCOc1ccccc1OCC(F)(F)F)C(=O)OC(C)(C)C
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