5'-​O-​[Bis(4-​methoxyphenyl)​phenylmethyl]​-​3'-​Thymidylic Acid Bis(2-​cyanoethyl) Ester

CAS: 76759-76-7

Ref. TR-B486705

Product Information

• Name: 5'-​O-​[Bis(4-​methoxyphenyl)​phenylmethyl]​-​3'-​Thymidylic Acid Bis(2-​cyanoethyl) Ester
• Synonyms: Bis(2-cyanoethyl) ((2R,3S,5R)-2-(Hydroxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl) Phosphate

Description

Applications 5'-​O-​[Bis(4-​methoxyphenyl)​phenylmethyl]​-​3'-​Thymidylic Acid Bis(2-​cyanoethyl) Ester is an intermediate in synthesizing Thymidine 5’-Triphosphate, 3’-Phosphate Triethylamine Salt (T410015), a derivative of Thymidine 5’-Triphosphate which is used for the biosynthesis of deoxyribonucleic acids by DNA polymerases and reverse transcriptases.
References Kim, D., et al.: J. Molecular Biol., 321, 807 (2002); Crampton, D., et al.: Molecular Cell, 21, 165 (2006)

• Brand: TRC

Chemical properties

• Molecular weight: 395.321
• Formula: C₁₆H₂₁N₄O₈P
• Color/Form: White Solid
• InChI: InChI=1S/C16H17N3O9/c20-7-10-9(21)5-13(27-10)18-6-8(15(25)17-16(18)26)1-4-14(24)28-19-11(22)2-3-12(19)23/h1,4,6,9-10,13,20-21H,2-3,5,7H2,(H,17,25,26)/b4-1+/t9-,10+,13+/m0/s1
• InChI key: InChIKey=UCFQDCCIRGUDBE-OJJONNAYSA-N
• SMILES: O=C(/C=C/c1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O)ON1C(=O)CCC1=O