Bis(2-thienyl) Ketone

CAS: 704-38-1

Ref. TR-B585365

Product Information

• Name: Bis(2-thienyl) Ketone
• Synonyms: Tiotropium Bromide Monohydrate Imp. F (EP), Tiotropium Bromide Imp. F (EP), Dithiophen-2-ylmethanone, Tiotropium Bromide Monohydrate Impurity F, Tiotropium Impurity F, Di-2-thienyl ketone, Bis(2-thienyl)ketone~Di-2-thienyl ketone, Dithiophen-2-Ylmethanone
• CAS: 704-38-1

Description

Impurity Tiotropium EP Impurity F
Applications Bis(2-thienyl) Ketone (Tiotropium EP Impurity F) can be used in the synthesis of antitumor agents via the formation of hydantoins. Also is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.
References Rodgers, T. et al.: J. Med. Chem., 20, 591 (1977); Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);

• Brand: TRC

Chemical properties

• Molecular weight: 194.27
• Formula: C₉H₆OS₂
• Color/Form: White to Light Grey Solid
• InChI: InChI=1S/C9H6OS2/c10-9(7-3-1-5-11-7)8-4-2-6-12-8/h1-6H
• InChI key: InChIKey=GUTQMBQKTSGBPQ-UHFFFAOYSA-N
• SMILES: O=C(c1cccs1)c1cccs1