N-Boc-N-methyl-D-phenylalanine

CAS: 85466-66-6

Ref. TR-B603045

Product Information

• Name: N-Boc-N-methyl-D-phenylalanine
• Synonyms: N-[(1,1-Dimethylethoxy)carbonyl]-N-methyl-D-phenylalanine, (R)-2-[N-Methyl-N-[(tert-butoxy)carbonyl]amino]-3-phenylpropanoic Acid, N-alpha-t-butyloxycabonyl-N-alpha-Methyl-D-phenylalanine, Boc-N-methyl-D-phenylalanine, Boc-D-Mephe-Oh
• CAS: 85466-66-6

Description

Applications N-Boc-N-methyl-D-phenylalanine acts as a reagent in the total solid-phase peptide synthesis of antibacterial Teixobactin and its comparison with natural product. Design, synthesis and in vitro anti-tumor activity of novel actinomycin D analogs. Total synthesis and reassignment of octapeptide tasiamide B, including its diastereomers and evaluation of their cytotoxicity in cancer cell lines
References Giltrap, A. M., et al.: Org. Letts., 18, 2788 (2016); Zhang, B., et al.: Gaodeng Xuexiao Huaxue Xuebao, 31, 1346 (2010)

• Brand: TRC

Chemical properties

• Molecular weight: 279.33
• Formula: C₁₅H₂₁NO₄
• Color/Form: Off-White Solid
• InChI: InChI=1S/C15H21NO4/c1-15(2,3)20-14(19)16(4)12(13(17)18)10-11-8-6-5-7-9-11/h5-9,12H,10H2,1-4H3,(H,17,18)/t12-/m1/s1
• InChI key: InChIKey=AJGJINVEYVTDNH-GFCCVEGCSA-N
• SMILES: CN(C(=O)OC(C)(C)C)[C@H](Cc1ccccc1)C(=O)O