(R)-1-Boc-3-hydroxypiperidine

CAS: 143900-43-0

Ref. TR-B656655

Product Information

• Name: (R)-1-Boc-3-hydroxypiperidine
• Synonyms: (3R)-3-Hydroxypiperidine-1-carboxylic Acid tert-Butyl Ester, (R)-3-Hydroxy-1-(tert-butoxycarbonyl)piperidine, (R)-3-Hydroxypiperidine-1-carboxylic Acid tert-Butyl Ester, (R)-tert-Butyl 3-hydroxy-1-piperidinecarboxylate, (R)-tert-Butyl 3-Hydroxypiperidine-1-carboxylate, tert-Butyl (3R)-3-hydroxypiperidine-1-carboxylate, 1-Piperidinecarboxylic Acid, 3-Hydroxy-, 1,1-Dimethylethyl Ester, (3R)-, Tert-Butyl (3R)-3-Hydroxypiperidine-1-Carboxylate, Ibrutinib Intermediate-1, (R)-tert-butyl 3-hydroxypiperidine-1-carboxylate
• CAS: 143900-43-0

Description

Applications (R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. (R)-1-Boc-3-hydroxypiperidine has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kikuchi, T., et. al.: J. Labelled Comptd. Rad., 44, 31 (2001); Isakovic, L., et. al.: Bioorg. Med. Chem. Lett., 19, 2742 (2009)

• Brand: TRC

Chemical properties

• Molecular weight: 201.26
• Formula: C₁₀H₁₉NO₃
• Color/Form: Neat
• InChI: InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-5-8(12)7-11/h8,12H,4-7H2,1-3H3/t8-/m1/s1
• InChI key: InChIKey=UIJXHKXIOCDSEB-MRVPVSSYSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC[C@@H](O)C1