3-Benzyl-6-bromo-2-chloroquinoline
CAS: 654655-68-2
Ref. TR-B674545
| 1g | Discontinued | ||
| 250mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
3-Benzyl-6-bromo-2-chloroquinoline
Synonyms:
- 6-Bromo-2-chloro-3-(phenylmethyl)quinoline
- 3-Benzyl-6-Bromo-2-Chloroquinoline
Description:
Applications 3-Benzyl-6-bromo-2-chloroquinoline is an intermediate in the synthesis of (αS,βR)-Bedaquiline (B119540), which is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References Cheepsattayakorn, A., et al.: Anti-Infect. Drug. Discover.,7, 141 (2012); de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
332.62
Formula:
C16H11BrClN
InChI:
InChI=1S/C16H11BrClN/c17-14-6-7-15-12(10-14)9-13(16(18)19-15)8-11-4-2-1-3-5-11/h1-7,9-10H,8H2
InChI key:
InChIKey=UGXUDVNBDYIJHJ-UHFFFAOYSA-N
SMILES:
Clc1nc2ccc(Br)cc2cc1Cc1ccccc1
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