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7-Bromoacetylaminocephalosporanic Acid
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7-Bromoacetylaminocephalosporanic Acid

CAS: 26973-80-8

Ref. TR-B679125

1g
1,933.00 €
100mg
283.00 €
Estimated delivery in United States, on Tuesday 2 Jul 2024

Product Information

Name:
7-Bromoacetylaminocephalosporanic Acid
Synonyms:
  • (6R-trans)-3-[(Acetyloxy)methyl]-7-[(bromoacetyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
  • 7-(2-Bromoacetamido)cephalosporanic Acid
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 3-[(acetyloxy)methyl]-7-[(bromoacetyl)amino]-8-oxo-, (6R,7R)- (9CI)
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,3-[(acetyloxy)methyl]-7-[(bromoacetyl)amino]-8-oxo-, (6R-trans)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-(2-bromoacetamido)-3-(hydroxymethyl)-8-oxo-, acetate (ester) (8CI)
  • 7-(2-Bromoacetamido)cephalosporanic acid
  • 7-Bromoacetylaminocephalosporanicacid
Description:

Applications An analog of glutaryl-7-amino cephalosporanic acid (GL-7-ACA). Can inhibit and specifically alkylate GL-7-ACA acylase (C130) from Pseudomonas sp.130 by forming a carbon-carbon bond between BA-7-ACA and the C-2 on indole ring of Trp-β4 residue of C130.
References Zhang, W. et al.; Biochem. Bioph. Res. Co. 313, 555 (2004); Huang, X. et al.; J. Biol. Chem. 277, 10256 (2002)

Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
393.21
Formula:
C12H13BrN2O6S
Color/Form:
Off-white Solid
InChI:
InChI=1S/C12H13BrN2O6S/c1-5(16)21-3-6-4-22-11-8(14-7(17)2-13)10(18)15(11)9(6)12(19)20/h8,11H,2-4H2,1H3,(H,14,17)(H,19,20)/t8-,11-/m1/s1
InChI key:
InChIKey=VDMWZOLTJWUSJT-LDYMZIIASA-N
SMILES:
CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)CBr)[C@H]2SC1
MDL:
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EINECS:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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