8-Bromo-3,7-dihydro-3-methyl-7-(phenylmethyl)-1H-purine-2,6-dione

CAS: 93703-26-5

Ref. TR-B683480

Product Information

• Name: 8-Bromo-3,7-dihydro-3-methyl-7-(phenylmethyl)-1H-purine-2,6-dione
• Synonyms: 7-benzyl-8-bromo-3-methylpurine-2,6-dione, 1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-3-methyl-7-(phenylmethyl)-

Description

Applications 8-Bromo-3,7-dihydro-3-methyl-7-(phenylmethyl)-1H-purine-2,6-dione,is a substituted derivative of Xanthine (X499950), found in animal organs, yeast, potatoes, coffee beans, tea. It can also be used for the synthesis of Linagliptin (L465900), which is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.
References Mueller, C. et. al: Handbook Exp. Pharmacol. 200,151(2011); Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011); Mtthias E., et. al: J. Med. Chem., 50, 6450 (2007);

• Brand: TRC

Chemical properties

• Molecular weight: 335.156
• Formula: C₁₃H₁₁BrN₄O₂
• Color/Form: Neat
• InChI: InChI=1S/C13H11BrN4O2/c1-17-10-9(11(19)16-13(17)20)18(12(14)15-10)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,16,19,20)
• InChI key: InChIKey=SFIWIEFIJQKWQZ-UHFFFAOYSA-N
• SMILES: Cn1c(=O)[nH]c(=O)c2c1nc(Br)n2Cc1ccccc1