2-Bromoethyl Methanethiosulfonate

CAS: 26139-15-1

Ref. TR-B684250

Product Information

• Name: 2-Bromoethyl Methanethiosulfonate
• Synonyms: 1-bromo-2-methylsulfonylsulfanylethane

Description

Applications Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. Useful for mapping the pore-lining regions of the ryanodine receptor.
References Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Holmgren, M. et al: Neuropharmacology, 35, 797 (1996) Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233, 606 (1997), Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1997), Rassendren, F., et al.: The EMBO Journal, 16, 3446 (1997), Egan, T.M., et al.: The Journal of Neuroscience, 18(7), 2350 (1998), Lin, C.-W. and Tsung-Yu, C.: J. Gen. Physiol., 116, 535 (2000)

• Brand: TRC

Chemical properties

• Molecular weight: 219.12
• Formula: C₃H₇BrO₂S₂
• Color/Form: Neat
• InChI: InChI=1S/C3H7BrO2S2/c1-8(5,6)7-3-2-4/h2-3H2,1H3
• InChI key: InChIKey=YMXDGRXCNRNUFC-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)SCCBr