Buclizine, Dihydrochloride

CAS: 129-74-8

Ref. TR-B689450

Product Information

• Name: Buclizine, Dihydrochloride
• Synonyms: Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, hydrochloride (1:2), Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, dihydrochloride (9CI), 1-(p-Chlorobenzhydryl)-4-(p-tert-butylbenzyl)diethylenediamine hydrochloride, 1-(p-tert-Butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazine dihydrochloride, 1-p-Chlorobenzhydryl-4-p-(t)-butylbenzylpiperazine dihydrochloride, Aphilan R, Bucladin S, Buclina, Buclizine hydrochloride, Buclodin, Histabutyzine hydrochloride, Longifene, NSC 25141, Softran, UCB 4445, Vibazine, Vibazine Hydrochloride, Piperazine, 1-(p-tert-butylbenzyl)-4-(p-chloro-alpha-phenylbenzyl)-, dihydrochloride (6CI,7CI,8CI), 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride, 1-(4-Tert-Butylbenzyl)-4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazine Dihydrochloride, Buclizine HCl, Buclizine Hydrochloride, Piperazine, 1-(p-tert-butylbenzyl)-4-(p-chloro-α-phenylbenzyl)-, dihydrochloride, Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, dihydrochloride, Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, hydrochloride (1:2), Ucb 4445

Description

Applications Used as an antiemetic.
References Jorgensen, P.B., et al.: Curr. Ther. Res., 16, 1276 (1974), Adam, E.I.: J. Int. Med. Res., 15, 71 (1987)

• Brand: TRC

Chemical properties

• Molecular weight: 505.95
• Formula: C₂₈H₃₃ClN₂ClH
• Color/Form: White
• InChI: 2*1H, , InChI=1S/C28H33ClN2.2ClH/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24, /h4-16,27H,17-21H2,1-3H3
• InChI key: InChIKey=SDBHDSZKNVDKNU-UHFFFAOYSA-N
• SMILES: CC(C)(C)c1ccc(CN2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)cc1.Cl.Cl