(4S)-4-Formyl-2,2-dimethyl-3-oxazolidinecarboxylic Acid 1,1-Dimethylethyl Ester

CAS: 102308-32-7

Ref. TR-B689730

Product Information

• Name: (4S)-4-Formyl-2,2-dimethyl-3-oxazolidinecarboxylic Acid 1,1-Dimethylethyl Ester
• Synonyms: 3-Oxazolidinecarboxylic acid, 4-formyl-2,2-dimethyl-, 1,1-dimethylethyl ester, (S)-(-)-Garner aldehyde, (4S)-4-Formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylic acid tert-butyl ester (4S)-4-Formyl-2,2-dimethyl-3-oxazolidinecarboxylic acid 1,1-dimethylethyl ester, (4S)-4-Formyl-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester, (S)-3-(tert-Butoxycarbonyl)-2,2-dimethyl-4-formyloxazolidine(S)-4-Formyl-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester,(S)-Garner aldehyde, (S)-Garner's aldehyde, (S)-tert-Butyl 4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate, 1,1-Dimethylethyl (S)-4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate, Garner's aldehydeN-tert-Butoxycarbonyl-L-serinal acetonide, tert-Butyl (4S)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate, tert-Butyl (S)-(-)-4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate, tert-Butyl (S)-4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate, Butoxycarbonylformyldimethyloxazolidine, (S)-()-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde, (S)-(-)-3-tert-Butoxycarbonyl-4-formyl-2,2-dimethyl-1,3-oxazolidine, tert-butyl (4S)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate, (S)-N-Boc-4-Formyl-2,2-Dimethyl-Oxazolidine

Description

Applications (4S)-4-Formyl-2,2-dimethyl-3-oxazolidinecarboxylic Acid 1,1-Dimethylethyl Ester is used to prepare γ-aminophosphonates (N-arylamide phosphonates as subtype-selective sphingosine 1-phosphate receptor agonists and antagonists. It is also used to synthesize N-sulfonylated propargylglycine derivatives as metalloproteinase inhibitors.
References Foss, F., et al.: Bioorg. Med. Chem., 15, 663 (2007); Natchus, M., et al.: J. Med. Chem., 44, 1060 (2001)

• Brand: TRC

Chemical properties

• Molecular weight: 229.27
• Formula: C₁₁H₁₉NO₄
• Color/Form: Clear Pale Yellow OIl
• InChI: InChI=1S/C9H9F/c10-9-5-4-7-2-1-3-8(7)6-9/h4-6H,1-3H2
• InChI key: InChIKey=XNSBRSZLJZUOJH-UHFFFAOYSA-N
• SMILES: Fc1ccc2c(c1)CCC2