2,3-Butanedione-d6 (Major)

CAS: 22026-37-5

Ref. TR-B690033

Product Information

• Name: 2,3-Butanedione-d6 (Major)
• Synonyms: 1,1,1,4,4,4-hexadeuteriobutane-2,3-dione, 2,3-Butanedione-d6(6CI), Biacetyl-d6, Dimethylglyoxal-d6

Description

Applications Labelled 2,3-Butanedione (B690030). 2,3-Butanedione (Diacetyl), the molecule implicated in the disease known as popcorn lung, has now been implicated in amyloid-β peptide toxicity associated with Alzheimer’s disease. Diacetyl accelerates amyloid-β aggregation-a hallmark of Alzheimer’s disease. These preliminary finding raise the possibility of long-term neurological toxicity mediated by DA.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wang, J., et al.: Exp. Neurol., 158, 328 (1999); Brown, M., et al.: Cell, 100, 391 (2000); Heinitz, K., et al.: J. Neurochem., 98, 1930 (2006); Brody, D., et al.: Science, 321, 1221 (2008); More, S., et al.: J. Med. Chem., 52, 4650 (2009);

• Brand: TRC

Chemical properties

• Molecular weight: 92.13
• Formula: C₄H₆O₂
• Color/Form: Yellow
• InChI: InChI=1S/C4H6O2/c1-3(5)4(2)6/h1-2H3/i1D3,2D3
• InChI key: InChIKey=QSJXEFYPDANLFS-WFGJKAKNSA-N
• SMILES: [2H]C([2H])([2H])C(=O)C(=O)C([2H])([2H])[2H]