24,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy-FK-506 (mixture of diastereomers)

CAS: 1356932-17-6

Ref. TR-B691090

Product Information

• Name: 24,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy-FK-506 (mixture of diastereomers)
• Synonyms: 24,33-Bis-O-(tert-butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy Tacrolimus

Description

Applications An intermediate in the preparation of labelled FK-506 (Tacrolimus)

• Brand: TRC

Chemical properties

• Molecular weight: 1066.55
• Formula: C₅₆H₉₉NO₁₄Si₂
• Color/Form: Light Grey Solid
• InChI: InChI=1S/C56H99NO14Si2/c1-34-25-35(2)27-47(66-13)50-48(67-14)29-37(4)56(64,69-50)51(61)52(62)57-24-20-19-21-42(57)53(63)68-49(36(3)28-39-22-23-44(46(30-39)65-12)70-72(15,16)54(6,7)8)38(5)45(71-73(17,18)55(9,10)11)32-43(60)40(26-34)31-41(59)33-58/h26,28,35,37-42,44-50,58-59,64H,19-25,27,29-33H2,1-18H3/b34-26-,36-28+/t35-,37+,38+,39-,40-,41?,42-,44+,45-,46-,47-,48+,49+,50+,56+/m0/s1
• InChI key: InChIKey=VVXLUGMPTYRRQJ-MGFFIHEWSA-N
• SMILES: CO[C@H]1C[C@H](/C=C(\C)[C@H]2OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@]3(O)O[C@H]([C@@H](OC)C[C@@H](C)C/C(C)=C/[C@@H](CC(O)CO)C(=O)C[C@H](O[Si](C)(C)C(C)(C)C)[C@H]2C)[C@H](OC)C[C@H]3C)CC[C@H]1O[Si](C)(C)C(C)(C)C