4-tert-Butyldimethylsilyl-5’-chloro-4a’-hydroxy Simvastatin
CAS: 123852-10-8
Ref. TR-B691170
5mg | Discontinued | ||
10mg | Discontinued | ||
25mg | Discontinued |
Product Information
Name:
4-tert-Butyldimethylsilyl-5’-chloro-4a’-hydroxy Simvastatin
Synonyms:
- 2,2-Dimethylbutanoic Acid [1S-[1α,3α,4β,4aα,7β,8β(2S*,4S*)]]-4-Chloro-8-[2-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,4,4a,7,8,8a-octahydro-4a-hydroxy-3,7-dimethyl-1-naphthalenyl Ester
- (1S,3R,4S,4aS,7S,8S,8aS)-8-{2-[(2R,4R)-4-{[tert-butyl(dimethyl)silyl]oxy}-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-4-chloro-4a-hydroxy-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl 2,2-dimethylbutanoate
Description:
Applications Intermediate for the preparation of Simvastatin analogs as HMG-CoA reductase inhibitors.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
585.29
Formula:
C31H53ClO6Si
Color/Form:
Off-White Solid
InChI:
InChI=1S/C31H53ClO6Si/c1-11-30(7,8)28(34)37-24-16-20(3)27(32)31(35)15-14-19(2)23(26(24)31)13-12-21-17-22(18-25(33)36-21)38-39(9,10)29(4,5)6/h14-15,19-24,26-27,35H,11-13,16-18H2,1-10H3/t19-,20+,21+,22+,23-,24-,26+,27-,31-/m0/s1
InChI key:
InChIKey=DUYDNPDLGLCXCC-FSYOVWAKSA-N
SMILES:
CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)[C@H](Cl)[C@]2(O)C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O[Si](C)(C)C(C)(C)C)CC(=O)O3)[C@@H]12
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