2’-O-tert-Butyl(dimethyl)silyl-7-O-triethylsilyl-2-debenzoyl-4-desacetyl Paclitaxel

CAS: 160768-75-2

Ref. TR-B692575

Product Information

• Name: 2’-O-tert-Butyl(dimethyl)silyl-7-O-triethylsilyl-2-debenzoyl-4-desacetyl Paclitaxel
• Synonyms: (alphaR,betaS)-beta-(Benzoylamino)-alpha-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6-(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-Dodecahydro-11,12,12b-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester, [2aR-[2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha]]-beta-(Benzoylamino)-alpha-[[(1,1-dimethylethyl)dimethylsilyl]oxy]benzenepropanoic Acid 6-(Acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11,12,12b-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester, Paclitaxel - In House Impurity

Description

Impurity Paclitaxel - In House Impurity
Applications 2’-O-tert-Butyl(dimethyl)silyl-7-O-triethylsilyl-2-debenzoyl-4-desacetyl Paclitaxel is an intermediate in the synthesis of Paclitaxel (P132500) related compound. Paclitaxel - In House Impurity.
References Gunatilaka, A.A.L., et al.: J. Org. Chem., 64, 2694 (1999); Georg, G.I., et al.: Tetrahedron. Lett., 35, 8931 (1994);

• Brand: TRC

Chemical properties

• Molecular weight: 936.29
• Formula: C₅₀H₇₃NO₁₂Si₂
• Color/Form: Pale Brown Foam
• InChI: InChI=1S/C10H16O2/c1-6(2)7-4-8(11)10(3)9(5-7)12-10/h7-9,11H,1,4-5H2,2-3H3/t7-,8+,9-,10?/m1/s1
• InChI key: InChIKey=OOALTXSJGCZLBF-WSSOQDAQSA-N
• SMILES: C=C(C)[C@@H]1C[C@H](O)C2(C)O[C@@H]2C1