(3S,4aS,8aS)-2-[(2R,3S)-3-tert-Butyloxycarbonylamino-2-hydroxy-4-phenylbutyl]-N-(1,1-dimethylethyl)decahydro-3-isoquinolinecarboxamide

CAS: 142580-65-2

Ref. TR-B693680

Product Information

• Name: (3S,4aS,8aS)-2-[(2R,3S)-3-tert-Butyloxycarbonylamino-2-hydroxy-4-phenylbutyl]-N-(1,1-dimethylethyl)decahydro-3-isoquinolinecarboxamide
• Synonyms: N-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-carbamic Acid 1,1-Dimethylethyl Ester, [3S-[2(1R*,2S*),3alpha,4abeta,8abeta]]-3-[3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-carbamic Acid 1,1-Dimethylethyl Ester, carbamic acid, N-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-, 1,1-dimethylethyl ester
• CAS: 142580-65-2

Description

Applications Intermediate in the preparation of HIV-1 protease inhibitors.
References Kiralj, R. & Ferreira, M.: J. Mol. Graph. Model., 21, 435 (2003); Maw, H. & Hall, L.: J. Chem. Inf. Comp. Sci., 42, 290 (2002); Lee, T. et al.: J. Am. Chem. Soc., 121, 1145 (1999)

• Brand: TRC

Chemical properties

• Molecular weight: 239.273
• Formula: C₂₉H₄₇N₃O₄
• Color/Form: Off-White to Pale Yellow Solid
• InChI: InChI=1S/C14H13N3O/c15-14-16-11-7-6-10(8-12(11)17-14)13(18)9-4-2-1-3-5-9/h1-8,13,18H,(H3,15,16,17)