4-[[(t-Butoxycarbonyl)amino]methyl]cyclohexanecarboxylic Acid

CAS: 162046-58-4

Ref. TR-B699895

Product Information

• Name: 4-[[(t-Butoxycarbonyl)amino]methyl]cyclohexanecarboxylic Acid
• Synonyms: 4-[[[(1,1-Dimethylethoxy)carbonyl]amino]methyl]cyclohexanecarboxylic Acid, Trans-4-(Tert-Butyloxycarbonylaminomethyl)-Cyclohexanoic Acid, 4-(Tert-Butoxycarbonylamino-Methyl)-Cyclohexanecarboxylic Acid, Iflab-Bb F2108-0060, Boc-Amc-Oh, Boc-4-Amc-Oh, Buttpark 52\04-68, Trans-4-(T-Butyloxycarbonylaminomethyl)-Cyclohexanoic Acid, 4-{[(Tert-Butoxycarbonyl)Amino]Methyl}Cyclohexanecarboxylic Acid
• CAS: 162046-58-4

Description

Applications 4-[[(t-Butoxycarbonyl)amino]methyl]cyclohexanecarboxylic Acid is an intermediate in synthesizing cis-Tranexamic Acid (T714500), which is antifibrinolytic agent; blocks lysine binding sites of plasminogen. Hemostatic.
References Andersson, et al.: Scand. J. Haematol. 2, 230 (1965); Melander, B., et al.: Acta Pharmacol. Toxicol., 22, 340 (1965); Bonnar, J., et al.: Br. Med. J., 313, 579 (1996); Dunn, C.J., et al.: Drugs, 57, 1005 (1999)

• Brand: TRC

Chemical properties

• Molecular weight: 257.33
• Formula: C₁₃H₂₃NO₄
• Color/Form: Off White Solid
• InChI: InChI=1S/C13H23NO4/c1-13(2,3)18-12(17)14-8-9-4-6-10(7-5-9)11(15)16/h9-10H,4-8H2,1-3H3,(H,14,17)(H,15,16)
• InChI key: InChIKey=OLAHOMJCDNXHFI-UHFFFAOYSA-N
• SMILES: COc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1