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5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione
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5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione

CAS: 830346-48-0

Ref. TR-B750323

1g
212.00 €
5g
778.00 €
10g
1,047.00 €
Estimated delivery in United States, on Wednesday 26 Jun 2024

Product Information

Name:
5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione
Synonyms:
  • 5-Bromo-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione
  • 1-[2-Fluoro-6-(trifluoromethyl)benzyl]-5-bromo-6-methyl-1H-pyrimidine-2,4-dione
  • 5-bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-4-hydroxy-6-methylpyrimidin-2(1H)-one
Description:

Applications 5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione is an intermediate in the synthesis of Elagolix, a gonadotropin-releasing hormone antagonist (GnRH) used in the treatment of endometriosis.
References Tukun, F. et al.: Molecules, 22, 12 (2017);

Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
381.12
Formula:
C13H9BrF4N2O2
Color/Form:
Neat
InChI:
InChI=1S/C13H9BrF4N2O2/c1-6-10(14)11(21)19-12(22)20(6)5-7-8(13(16,17)18)3-2-4-9(7)15/h2-4H,5H2,1H3,(H,19,21,22)
InChI key:
InChIKey=RDQPTRWUBKZZFJ-UHFFFAOYSA-N
SMILES:
Cc1c(Br)c(=O)[nH]c(=O)n1Cc1c(F)cccc1C(F)(F)F
MDL:
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EINECS:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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