tert-Butyl 4-Iodobutyrate

CAS: 6182-78-1

Ref. TR-B809470

Product Information

• Name: tert-Butyl 4-Iodobutyrate
• Synonyms: tert-butyl 4-iodobutanoate

Description

Applications tert-Butyl 4-Iodobutyrate is a versatile reactant used in the preparation of phosphorylated 3-heteroarylcoumarins that are employed in fluorescence microscopy and nanoscopy. It is also used in the preparation of α-Me α-carboxyalkyl amino acids that can be incorporated into phosphotyrosine-free peptides as Grb2 SH2-inhibitors and potential anticancer agents.
References Long, Y., et al.: J. Med. Chem., 51, 6371 (2008); Nizamov, S., et al.: Chem. Eur. J., 18, 16339 (2012);

• Brand: TRC

Chemical properties

• Molecular weight: 270.108
• Formula: C₈H₁₅IO₂
• Color/Form: Neat
• InChI: InChI=1S/C8H15IO2/c1-8(2,3)11-7(10)5-4-6-9/h4-6H2,1-3H3
• InChI key: InChIKey=JOCPIDVCNQGZGA-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)CCCI