2-Butynoic Acid

CAS: 590-93-2

Ref. TR-B809725

Product Information

• Name: 2-Butynoic Acid
• Synonyms: Tetrolic Acid, 1-Propynecarboxylic Acid, 3-Methylpropiolic Acid, Methylacetylenecarboxylic Acid, Methylpropiolic Acid, Methylpropynoic Acid, NSC 174116, 1-Propynecarboxylic acid, 3-Methylpropiolic acid, But-2-Ynoate, But-2-Ynoic Acid, Methylacetylenecarboxylic acid, Methylpropiolic acid, Methylpropynoic acid, Nsc 174116, Tetrolic acid
• CAS: 590-93-2

Description

Applications 2-Butynoic Acid is used as a reagent in the synthesis of BMS 911543 (B596075); a potent JAK2 inhibitor used as a potential treatment for myeloproliferative disorders. 2-Butynoic Acid is also used in the preparation of chirally pure 1,2,3,4-tetrahydroisoquinoline analogs as anti-cancer agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fitzgerald, M.A., et al.: J. Org. Chem., 80, 6001 (2015); Ramanivas, T., et al.: Eur. J. Med. Chem., 92, 608 (2015)

• Brand: TRC

Chemical properties

• Molecular weight: 84.07
• Formula: C₄H₄O₂
• Color/Form: Neat
• InChI: InChI=1S/C4H4O2/c1-2-3-4(5)6/h1H3,(H,5,6)
• InChI key: InChIKey=OTMSDBZUPAUEDD-UHFFFAOYSA-N
• SMILES: CC#CC(=O)O