2,3-Bis((tert-Butyldimethylsilyl)oxy)-2-hydroxy Estrone 6-N3-Adenine
Ref. TR-B942743
| 5mg | Discontinued | ||
| 10mg | Discontinued | ||
| 2500µg | Discontinued |
Product Information
Name:
2,3-Bis((tert-Butyldimethylsilyl)oxy)-2-hydroxy Estrone 6-N3-Adenine
Description:
Applications 2,3-Bis((tert-Butyldimethylsilyl)oxy)-2-hydroxy Estrone 6-N3-Adenine is an intermediate in the synthesis of 4-Hydroxy Estradiol 1-N3-Adenine which is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.
References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
648
Formula:
C35H53N5O3Si2
Color/Form:
Light Brown
InChI:
InChI=1S/C35H53N5O3Si2/c1-33(2,3)44(8,9)42-27-17-22-21-14-15-35(7)25(12-13-29(35)41)23(21)16-26(40-20-39-31(36)30-32(40)38-19-37-30)24(22)18-28(27)43-45(10,11)34(4,5)6/h17-21,23,25-26H,12-16,36H2,1-11H3/t21-,23-,25+,26?,35+/m1/s1
InChI key:
InChIKey=GXANMBISFKBPEX-ARJAWSKDSA-N
SMILES:
CC/C=C\CC=O
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