Capecitabine-2',3'-cyclic Carbonate

CAS: 921769-65-5

Ref. TR-C175660

Product Information

• Name: Capecitabine-2',3'-cyclic Carbonate
• Synonyms: 2',3'-O-Carbonyl-5'-deoxy-5-fluoro-N4-(pentyloxycarbonyl)cytidine, Capecitabine Related Compound C, Capecitabine Impurity F
• CAS: 921769-65-5

Description

Impurity Capecitabine EP Impurity F/ USP Capecitabine Related Compound C
Applications Capecitabine-2',3'-cyclic Carbonate (Capecitabine EP Impurity F) is a capecitabine related compound C is an impurity in Capecitabine (C175650), an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).
References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 385.34
• Formula: C₁₆H₂₀FN₃O₇
• Color/Form: White Solid
• InChI: InChI=1S/C16H20FN3O7/c1-3-4-5-6-24-15(22)19-12-9(17)7-20(14(21)18-12)13-11-10(8(2)25-13)26-16(23)27-11/h7-8,10-11,13H,3-6H2,1-2H3,(H,18,19,21,22)/t8-,10-,11-,13-/m1/s1
• InChI key: InChIKey=VTAMAYSBXXKQPB-IZSYJUOESA-N
• SMILES: CCCCCOC(=O)Nc1nc(=O)n([C@@H]2O[C@H](C)C3OC(=O)O[C@@H]32)cc1F