2-(4-(2-(4-(Carboxymethoxy)-2,3-dichlorobenzoyl)-2,5-diethyl-3,4-dihydro-2H-pyran-6-yl)-2,3-dichlorophenoxy)acetic Acid

CAS: 25355-92-4

Ref. TR-C178680

Product Information

• Name: 2-(4-(2-(4-(Carboxymethoxy)-2,3-dichlorobenzoyl)-2,5-diethyl-3,4-dihydro-2H-pyran-6-yl)-2,3-dichlorophenoxy)acetic Acid
• Synonyms: 2-[4-[2-[4-(carboxymethoxy)-2,3-dichlorobenzoyl]-2,5-diethyl-3,4-dihydropyran-6-yl]-2,3-dichlorophenoxy]acetic acid

Description

Stability Hygroscopic
Applications 2-(4-(2-(4-(Carboxymethoxy)-2,3-dichlorobenzoyl)-2,5-diethyl-3,4-dihydro-2H-pyran-6-yl)-2,3-dichlorophenoxy)acetic Acid is an impurity of Ethacrynic Acid (E676000), a diuretic used to treat high blood pressure and swelling caused by congestive heart failure, liver failure and kidney failure.
References Goerlitzer, K., et. al.: Archiv Der Pharmazie, 316, 355 (1983); Beyer, et al.: J. Pharmacol. Exp. Ther., 147, 1 (1965); Kim., et al.: Am. J. Cardiol., 27, 407 (1971); Williamson, H.E., et al.: J. Clin. Pharmacol., 17, 663 (1977)

• Brand: TRC

Chemical properties

• Molecular weight: 606.28
• Formula: C₂₆H₂₄Cl₄O₈
• Color/Form: Neat
• InChI: InChI=1S/C26H24Cl4O8/c1-3-13-9-10-26(4-2,25(35)15-6-8-17(23(30)21(15)28)37-12-19(33)34)38-24(13)14-5-7-16(22(29)20(14)27)36-11-18(31)32/h5-8H,3-4,9-12H2,1-2H3,(H,31,32)(H,33,34)
• InChI key: InChIKey=SMYPMBZGOORDNT-UHFFFAOYSA-N
• SMILES: CCC1=C(c2ccc(OCC(=O)O)c(Cl)c2Cl)OC(CC)(C(=O)c2ccc(OCC(=O)O)c(Cl)c2Cl)CC1