(+)-Chloro(p-menth-3-yloxy)dimethylsilane
CAS: 19470-77-0
Ref. TR-C194705
| 1g | Discontinued | ||
| 100mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
(+)-Chloro(p-menth-3-yloxy)dimethylsilane
Synonyms:
- [1R-(1α,2β,5α)]-Chlorodimethyl[[5-methyl-2-(1-methylethyl)cyclohexyl]oxy]silane
Description:
Applications (+)-Chloro(p-menth-3-yloxy)dimethylsilane is a byproduct in the synthesis of Carfilzomib (2R,4R)-Diol (C183525), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
248.86
Formula:
C12H25ClOSi
Color/Form:
Liquid
InChI:
InChI=1S/C12H25ClOSi/c1-9(2)11-7-6-10(3)8-12(11)14-15(4,5)13/h9-12H,6-8H2,1-5H3/t10-,11+,12-/m1/s1
InChI key:
InChIKey=JXZSEZCMUZKNCK-GRYCIOLGSA-N
SMILES:
CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O[Si](C)(C)Cl
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