(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile

CAS: 565452-98-4

Ref. TR-C363785

Product Information

• Name: (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
• Synonyms: (2R)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile

Description

Applications (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.
References Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008); Villhauer, E. B., et al.: J. Med. Chem., 46, 2774 (2003);

• Brand: TRC

Chemical properties

• Molecular weight: 172.61
• Formula: C₇H₉ClN₂O
• Color/Form: Neat
• InChI: InChI=1S/C7H9ClN2O/c8-4-7(11)10-3-1-2-6(10)5-9/h6H,1-4H2/t6-/m1/s1
• SMILES: N#C[C@H]1CCCN1C(=O)CCl