2-Chloro-1-(3,4-dihydroxyphenyl)ethanone-d5

CAS: 2732868-75-4

Ref. TR-C365327

Product Information

• Name: 2-Chloro-1-(3,4-dihydroxyphenyl)ethanone-d5
• Synonyms: 2-Chloro-3',4'-dihydroxyacetophenone-d5, 1-Chloroacetyl-3,4-dihydroxybenzene-d5, 2-Chloro-1-(3,4-dihydroxyphenyl)-1-ethanone-d5, 3,4-Dihydroxyphenacyl Chloride-d5, Chloro Acetyl Catechol-d5
• CAS: 2732868-75-4

Description

Applications 2-Chloro-1-(3,4-dihydroxyphenyl)ethanone-d5 is a labelled analogue of 2-Chloro-1-(3,4-dihydroxyphenyl)ethanone (C365325) and an intermediate in synthesizing DL-Norepinephrine-d6 Hydrochloride 85% (N674502), which is an antagonist of dibutyryl cyclic AMP in the regulation of narcosis. Norepinephrine modulates human dendritic cell activation by altering cytokine release.
References Piguet, P., et al.: J. Exp. Med., 173, 673 (1991), Hosoi, J., et al.: Nature, 363, 159 (1993), Elenkov, I., et al.: Pharmacol. Rev., 52, 595 (2000), Kaplan, D., et al.: Immunity, 23, 611 (2005),

• Brand: TRC

Chemical properties

• Molecular weight: 191.62
• Formula: C₈H₂D₅ClO₃
• Color/Form: Off-White Solid
• InChI: InChI=1S/C8H7ClO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,10-11H,4H2/i1D,2D,3D,4D2
• InChI key: InChIKey=LWTJEJCZJFZKEL-QUWGTZMWSA-N
• SMILES: [2H]c1c([2H])c(C(=O)C([2H])([2H])Cl)c([2H])c(O)c1O