2-Chloro-2’,3’-O-isopropylideneadenosine-5’-N-ethylcarboxamide

CAS: 120225-75-4

Ref. TR-C367370

Product Information

• Name: 2-Chloro-2’,3’-O-isopropylideneadenosine-5’-N-ethylcarboxamide
• Synonyms: (3aR,4R,6S,6aS)-4-(6-amino-2-chloropurin-9-yl)-N-ethyl-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole-6-carboxamide, 1-(6-Amino-2-chloro-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-β-<span class="text-smallcaps">D</span>-ribofuranuronamide, 2-Chloro-23O-isopropylideneadenosine-5N-ethylcaboxamide, Furo[3,4-d]-1,3-dioxole, β-<span class="text-smallcaps">D</span>-ribofuranuronamide deriv., β-<span class="text-smallcaps">D</span>-Ribofuranuronamide, 1-(6-amino-2-chloro-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-, Furo[3,4-d]-1,3-dioxole, β-D-ribofuranuronamide deriv., 1-(6-Amino-2-chloro-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide, β-D-Ribofuranuronamide, 1-(6-amino-2-chloro-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-

Description

Applications 2-Chloro-2’,3’-O-isopropylideneadenosine-5’-N-ethylcarboxamide is a potent and selective adenosine receptor agonist (1). It is also used to prepare photoreactive 2-​phenethylamine derivatives (2).
References (1) Hutchison, A.J., et al.: J. Med. Chem., 33, 1919 (1990)(2) Murai, Y., et al.: Eur. J. Org. Chem 2013, 2428 (2013)

• Brand: TRC

Chemical properties

• Molecular weight: 382.80
• Formula: C₁₅H₁₉ClN₆O₄
• Color/Form: Neat
• InChI: InChI=1S/C15H19ClN6O4/c1-4-18-12(23)8-7-9(26-15(2,3)25-7)13(24-8)22-5-19-6-10(17)20-14(16)21-11(6)22/h5,7-9,13H,4H2,1-3H3,(H,18,23)(H2,17,20,21)/t7-,8+,9-,13-/m1/s1
• InChI key: InChIKey=CHPHKXXDQSHQKC-LOKDSWTASA-N
• SMILES: CCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)nc(Cl)nc32)[C@@H]2OC(C)(C)O[C@H]12