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1-[2-[(4-Chloro-2,5-dimethylphenyl)thio]phenyl]-piperazine
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1-[2-[(4-Chloro-2,5-dimethylphenyl)thio]phenyl]-piperazine

CAS: 2514952-66-8

Ref. TR-C371580

10mg
376.00 €
25mg
717.00 €
50mg
1,337.00 €
Estimated delivery in United States, on Wednesday 29 May 2024

Product Information

Name:
1-[2-[(4-Chloro-2,5-dimethylphenyl)thio]phenyl]-piperazine
Controlled Product
Synonyms:
  • 1-[2-[(4-Chloro-2,5-dimethylphenyl)thio]phenyl]piperazine (ACI)
Description:

Applications 1-[2-[(4-Chloro-2,5-dimethylphenyl)thio]phenyl]-piperazine is an intermediate in the synthesis of 3-Chloro-Vortioxetine which is an impurity of Vortioxetine (V766000), a multimodal serotonergic agent. Vortioxetine inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.
References Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)

Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
332.89
Formula:
C18H21ClN2S
Color/Form:
Beige Solid
InChI:
InChI=1S/C18H21ClN2S/c1-13-12-18(14(2)11-15(13)19)22-17-6-4-3-5-16(17)21-9-7-20-8-10-21/h3-6,11-12,20H,7-10H2,1-2H3
InChI key:
InChIKey=XBCXJKGHPABGSD-UHFFFAOYSA-N
SMILES:
Cn1ccc(=O)[nH]c1=O
MDL:
Melting point:
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Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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