1-[2-[(4-Chloro-2,5-dimethylphenyl)thio]phenyl]-piperazine
CAS: 2514952-66-8
Ref. TR-C371580
10mg | 376.00 € | ||
25mg | 717.00 € | ||
50mg | 1,337.00 € |
Product Information
- 1-[2-[(4-Chloro-2,5-dimethylphenyl)thio]phenyl]piperazine (ACI)
Applications 1-[2-[(4-Chloro-2,5-dimethylphenyl)thio]phenyl]-piperazine is an intermediate in the synthesis of 3-Chloro-Vortioxetine which is an impurity of Vortioxetine (V766000), a multimodal serotonergic agent. Vortioxetine inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.
References Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)
Chemical properties
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