![discount label](https://static.cymitquimica.com/public/img/discount.png)
(3S,4R)-N-(Chloro(4-nitrophenyl)methyl)-3-(3,4-dimethoxyphenyl)-1-methylpiperidin-4-amine
Ref. TR-C374175
10mg | 1,941.00 € | ||
500µg | 341.00 € | ||
2500µg | 580.00 € |
Product Information
- (3R,4R)-N-[chloro-(4-nitrophenyl)methyl]-3-(3,4-dimethoxyphenyl)-1-methylpiperidin-4-amine
Applications (3S,4R)-N-(Chloro(4-nitrophenyl)methyl)-3-(3,4-dimethoxyphenyl)-1-methylpiperidin-4-amine is an intermediate in the synthesis of Tolafentrine (T531000), which is a dual-selective phosphodiesterase 3/4 inhibitor used in chronic experimental pulmonary hypertension.
References Huxtable, R., et al.: Pharmacol. Ther., 47, 371 (1990), Tanaka, K., et al.: Cancer Res., 55, 2927 (1995), Wagner, R., et al.: J. Pharmacol. Exp. Ther., 282, 1650 (1997), Cowan, K., et al.: Nat. Med., 6, 698 (2000), Shankavaram, U., et al.: J. Biol. Chem., 276, 19027 (2001),
Chemical properties
Technical inquiry about: TR-C374175 (3S,4R)-N-(Chloro(4-nitrophenyl)methyl)-3-(3,4-dimethoxyphenyl)-1-methylpiperidin-4-amine
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.