2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane

CAS: 3308-94-9

Ref. TR-C380430

Product Information

• Name: 2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane
• Synonyms: 1,1-(Ethylenedioxy)-4-chloro-1-(4-fluorophenyl)butane, 1-(4-Fluorophenyl)-4-chlorobutan-1-one Ethylene Ketal, 1-Chloro-4,4-(ethylenedioxy)-4-(4-fluorophenyl)butane, 2-(3-Chloropropyl)-2-(4-fluorophenyl)dioxolane, 2-(3-Chloropropyl)-2-(p-fluorophenyl)-1,3-dioxolane, 2-(3-Chloropropyl)-2-(p-fluorophenyl)dioxolane, 2-(4-Fluorophenyl)-2-(3-chloropropyl)-1,3-dioxolane, 3-Chloropropyl 4-Fluorophenyl Ketone Ethylene Ketal, 3-p-Fluorobenzoylpropyl Chloride Ethylene Ketal, 4,4-(Ethylenedioxy)-4-(4-fluorophenyl)butyl Chloride, 4-(4-Fluorophenyl)-4,4-ethylenedioxy-1-chlorobutane, 4-(p-Fluorophenyl)-4,4-ethylenedioxy-1-chlorobutane, 4-Chloro-1,1-ethylenedioxy-1-(4-fluorophenyl)butane, 4-Chloro-1-(p-fluorophenyl)-1-butanone Cyclic Ethylene Acetal, 4, 1,3-Dioxolane, 2-(3-chloropropyl)-2-(4-fluorophenyl)-, 1,3-Dioxolane, 2-(3-chloropropyl)-2-(p-fluorophenyl)-, 1-(4-Fluorophenyl)-4-chlorobutan-1-one ethylene ketal, 3-Chloropropyl 4-fluorophenyl ketone ethylene ketal, 3-p-Fluorobenzoylpropyl chloride ethylene ketal, 4,4-(Ethylenedioxy)-4-(4-fluorophenyl)butyl chloride, 4-(3-Chloropropyl)-4-(4-Fluorophenyl)-1,3-Dioxolane, 4-Chloro-1-(p-fluorophenyl)-1-butanone cyclic ethylene acetal, 4-Chloro-4′-fluorobutyrophenone cyclic ethylene ketal, 4-Chloro-p-fluorobutyrophenone cyclic ethylene acetal, 4′-Fluoro-4-chlorobutyrophenone ethylene ketal

Description

Applications 2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane is used as a reagent to synthesize Piperidine (P479985) receptor ligands, compounds that have potential antipsychotic activity. 2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane is also used as a reagent to synthesize Bromoperidol, a neuroleptic drug that is closely related to Haloperidol (H103700).
References Gilligan, P., et al.: J. Med. Chem., 35, 4344 (1992); McCarrick, M. & Kollman, P.: J. Comp. Mol. Des., 13, 109 (1999); Niemegeers, C. & Janssen, P.: Arz.-Fors., 24, 45 (1974)

• Brand: TRC

Chemical properties

• Molecular weight: 244.69
• Formula: C₁₂H₁₄ClFO₂
• Color/Form: Neat
• InChI: InChI=1S/C12H14ClFO2/c13-7-1-6-12(15-8-9-16-12)10-2-4-11(14)5-3-10/h2-5H,1,6-9H2
• InChI key: InChIKey=FXFDJSQOCVDXBX-UHFFFAOYSA-N
• SMILES: Fc1ccc(C2(CCCCl)OCCO2)cc1