3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene

CAS: 23964-56-9

Ref. TR-C380873

Product Information

• Name: 3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene
• Synonyms: Methyl 3-(2-chloropropanoylamino)-4-methyl-2-thiophenecarboxylate
• CAS: 23964-56-9

Description

Applications 3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene is an intermediate in the synthesis of Articaine-d7 Hydrochloride which is the labelled form of Articaine Hydrochloride (A777905). Articaine Hydrochloride is the Hydrochloride Salt of Articaine (A777900). Articaine is an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand, food surgery and in dentistry.
References Malamed, S.F., et al.: J. Am. Dent. Assoc., 132, 177 (2001); Luan, F., et al.: Bioorg. Med. Chem., 21, 1870 (2013)

• Brand: TRC

Chemical properties

• Molecular weight: 261.73
• Formula: C₁₀H₁₂ClNO₃S
• Color/Form: White Solid
• InChI: InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)
• InChI key: InChIKey=DDOQBQRIEWHWBT-UHFFFAOYSA-N
• SMILES: NC(CCP(=O)(O)O)C(=O)O