Estimated delivery in United States, on Thursday 30 May 2024
Product Information
Name:
CIL56
Synonyms:
- CA3
- 2,7-bis(piperidinosulfonyl)-9H-fluoren-9-one oxime
CAS:
Description:
Applications CIL56 inhibits YAP/Tead transcriptional activity. Has anti-tumour effects on oesophageal adenocarcinoma with therapeutic potential in combination with 5-FU. Involved in ferroptosis, mediated by iron-dependent ROS.
References Dixon, Scott J., et al.: ACS Chemical Biology., 10, 1604 (2015); Shimada, Kenichi., et al.; Nature Chemical Biology., 12, 497 (2016)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
489.61
Formula:
C23H27N3O5S2
Color/Form:
White to Off-White Solid
InChI:
InChI=1S/C23H27N3O5S2/c27-24-23-21-15-17(32(28,29)25-11-3-1-4-12-25)7-9-19(21)20-10-8-18(16-22(20)23)33(30,31)26-13-5-2-6-14-26/h7-10,15-16,27H,1-6,11-14H2
InChI key:
InChIKey=XYZXEEIUKQGUHB-UHFFFAOYSA-N
SMILES:
O=S(=O)(c1ccc2c(c1)C(=NO)c1cc(S(=O)(=O)N3CCCCC3)ccc1-2)N1CCCCC1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-C433128 CIL56
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