Cletoquine-d4

CAS: 4298-15-1

Ref. TR-C573507

Product Information

• Name: Cletoquine-d4
• Synonyms: 2-[[4-[(7-Chloro-4-quinolyl)amino]pentyl]amino]ethanol-d4, (±)-Desethylhydroxychloroquine-d4, Desethylhydroxychloroquine-d4, 2-((4-((7-Chloro-4-quinolyl)amino)pentyl)amino)ethanol, 2-({4-[(7-Chloroquinolin-4-Yl)Amino]Pentyl}Amino)Ethanol, 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]amino]ethanol, Cletochina, Cletochina [DCIT], Cletoquina, Cletoquina [INN-Spanish], Cletoquine [INN:BAN], Cletoquinum, Cletoquinum [INN-Latin], Desethylhydroxychloroquine, Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]amino]-, Ethanol, 2-[[4-[(7-chloro-4-quinolyl)amino]pentyl]amino]-, Unii-83Cvd213Tu
• CAS: 4298-15-1

Description

Applications Cletoquine-d4 is the isotope labelled analog of Cletoquine, which is a metabolite of Hydroxychloroquine (H916900), an antimalarial; antirheumatic; lupus erythematosus suppressant.
References Yarden, Y., et al.: Nature, 323, 226 (1986); Seifert, R., et al.: J. Biol. Chem., 264, 8771 (1989); Gahl, W., et al.: Mol. Genet. Metab., 76, 234 (2002); Card, J., et al.: Toxicol. Sci., 75, 169 (2003)

• Brand: TRC

Chemical properties

• Molecular weight: 311.84
• Formula: C₁₆H₁₈D₄ClN₃O
• Color/Form: Neat
• InChI: InChI=1S/C16H22ClN3O/c1-12(3-2-7-18-9-10-21)20-15-6-8-19-16-11-13(17)4-5-14(15)16/h4-6,8,11-12,18,21H,2-3,7,9-10H2,1H3,(H,19,20)/i2D2,7D2
• InChI key: InChIKey=XFICNUNWUREFDP-BRVWLQDISA-N
• SMILES: [2H]C([2H])(CC(C)Nc1ccnc2cc(Cl)ccc12)C([2H])([2H])NCCO