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Cobicistat-d8
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Cobicistat-d8

CAS: 1004316-88-4

Ref. TR-C633152

Estimated delivery in United States, on Thursday 17 Dec 2020

Product Information

Name:
Cobicistat-d8
Synonyms:
  • (3R,6R,9S)-2-Methyl-13-[2-(1-methylethyl)-4-thiazolyl]-9-[2-(4-morpholinyl)ethyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic-d8 Acid 5-Thiazolylmethyl Ester
Description:

Applications Isotope labelled analogue of Cobicistat (C633150), a HIV protease inhibitor and have been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer, significantly increasing their plasma concentrations.
References Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012); Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012); Orr, S.T.M., et al.: J. Med. Chem., 55, 4896 (2012);

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Chemical properties

Molecular weight:
784.07
Formula:
C40H46D8N7O5S2
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Hazard Info

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