Coenzyme A S-Pyrazinecarboxylate Trisodium Salt

CAS: 85-61-0

Ref. TR-C636415

Product Information

• Name: Coenzyme A S-Pyrazinecarboxylate Trisodium Salt
• Synonyms: S-(2-(3-((2R)-4-(((((((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)-2-hydroxy-3,3-dimethylbutanamido)propanamido)ethyl) Pyrazine-2-carbothioate Trisodium Salt, <span class="text-smallcaps">D</span>-Coenzyme A, Adenosine 5'-(trihydrogen diphosphate) 3'-(dihydrogen phosphate) P'-[(R)-3-hydroxy-4-[[3-[(2-mercaptoethyl)amino]-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl] ester, Adenosine 5'-(trihydrogen diphosphate), 3'-(dihydrogen phosphate), P'-[3-hydroxy-4-[[3-[(2-mercaptoethyl)amino]-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl] ester, (R)-, Aluzime, COA, CoASH, Coa-Sh, Coalip, Coenzym A, Coenzyme A Free Acid From Yeast, Coenzyme A Hydrate, Coenzyme A, free acid, lyophilized, 75%, Coenzyme A, free acid, lyophilized, min. 75% (enzym.), Coenzyme ASH, Coenzyme a, free acid, D-Coenzyme A, Lucina, Reduced CoA, Thiol-CoA, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen diphosphate (non-preferred name), [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3S)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen diphosphate (non-preferred name), [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl 3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen diphosphate (non-preferred name), coenzima A, Coenzyme A

Description

Applications Coenzyme A S-Pyrazinecarboxylate is a derivative of Coenzyme A (C636400); a cofactor in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase.
References Strickland K.C. et al.: J. Biol. Chem., 285, 1627 (2010); Elovson J. et al.: J. Biol. Chem., 243, 3603 (1968)

• Brand: TRC

Chemical properties

• Molecular weight: 939.56
• Formula: C₂₆H₃₅N₉Na₃O₁₇P₃S
• Color/Form: Neat
• InChI: InChI=1S/C26H38N9O17P3S.3Na/c1-26(2,20(38)23(39)31-4-3-16(36)30-7-8-56-25(40)14-9-28-5-6-29-14)11-49-55(46,47)52-54(44,45)48-10-15-19(51-53(41,42)43)18(37)24(50-15)35-13-34-17-21(27)32-12-33-22(17)35;;;/h5-6,9,12-13,15,18-20,24,37-38H,3-4,7-8,10-11H2,1-2H3,(H,30,36)(H,31,39)(H,44,45)(H,46,47)(H2,27,32,33)(H2,41,42,43);;;/q;3*+1/p-3/t15-,18?,19?,20-,24-;;;/m1.../s1
• InChI key: InChIKey=XMXPRNZMONKUBQ-QSYHLCOKSA-K
• SMILES: CC(C)(COP(=O)(O[Na])OP(=O)(O[Na])OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C(O)C1OP(=O)(O)O[Na])[C@H](O)C(=O)NCCC(=O)NCCSC(=O)c1cnccn1