Conessine

CAS: 546-06-5

Ref. TR-C670500

Product Information

• Name: Conessine
• Synonyms: N,18-Dihydrotrimethylconkurchine, Conessin, NSC 119994, Neriine, N',18-Dihydro-N,N,N'-trimethylconkurchine, Roquessine, Wrightine, (3β)-N,N-Dimethylcon-5-enin-3-amine, 3β-(Dimethylamino)con-5-enine, (3-beta)-N,N-Dimethylcon-5-enin-3-amine, (3alpha,8xi,9xi,10alpha,14xi,17beta)-N,N-dimethylcon-5-enin-3-amine, (3beta,8xi,9xi,14xi,17xi)-N,N-dimethylcon-5-enin-3-amine, 1H-Naphth[2′,1′:4,5]indeno[1,7a-c]pyrrole, con-5-enin-3-amine deriv., 3beta-(Dimethylamino)con-5-ene, 3beta-(Dimethylamino)con-5-enine, Brn 4702160, Con-5-enin-3-amine, N,N-dimethyl-, (3beta)- (9CI), Con-5-enin-3-amine, N,N-dimethyl-, (3β)-, Con-5-enine, 3beta-(dimethylamino)- (8CI), Con-5-enine, 3β-(dimethylamino)-, Conesina, Conesina [INN-Spanish], Conessine [INN], Conessinum, Conessinum [INN-Latin], Conkurchine, N,18-dihydrotrimethyl-, Conkurchine, N,18-dihydrotrimethyl- (7CI), Konessin, N,N-dimethylcon-5-enin-3-amine, Nsc 119994, N′,18-Dihydro-N,N,N′-trimethylconkurchine, Unii-Ez38J9Bbdf

Description

Applications Conessine is a steroidal dibasic alkaloid with a rigid steroid-based skeleton. Conessine is a potent and selective histamine H3 receptor antagonist.
References Cowart, M. et al.: Inflam. Res., 46, S47 (2007); Dadoun, H. et al.: Ann. Pharm. Franc., 31, 237 (1973);

• Brand: TRC

Chemical properties

• Molecular weight: 356.59
• Formula: C₂₄H₄₀N₂
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C24H40N2/c1-16-20-8-9-22-19-7-6-17-14-18(25(3)4)10-12-23(17,2)21(19)11-13-24(20,22)15-26(16)5/h6,16,18-22H,7-15H2,1-5H3/t16-,18-,19+,20+,21-,22-,23-,24-/m0/s1
• InChI key: InChIKey=GPLGAQQQNWMVMM-MYAJQUOBSA-N
• SMILES: C[C@H]1[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](N(C)C)CC[C@]5(C)[C@H]4CC[C@]23CN1C